Hi, I use fleece with 2 layers of uhaul furniture pads (I have used my pads for 16 months now, best purchase ever!) and then I have a 1x2 grid sized litter/hay box with Carefresh. The two parts are separate coroplast boxes, so they hop from one into the other, keeping the carefresh off the fleece. It also helps because I can lift the 1x2 box out of the cage, dump it out in the trash can, wipe and replace the carefresh in minutes.
The fleece I use covers a 2x4 grid area. Every morning and evening I lift take the igloos and tunnels out and lift the fleece up and shake the poopies to the middle, and then I do the same with the other side, leaving a line of poop in the middle of the fleece that I quickly sweep up. I also move the igloos to a dry spot every day.
I clean my cage once a week, it starts smelling a little on day 6, but in the summer when it's warm the uhaul blankets seem to dry out faster, and I've gone 2 weeks in the summer.
I think Carefresh is a gift from above! LOL! I'm always shocked at how my litter boxes don't stink, but as soon as you dump it in the trash and everything is exposed the smell just explodes!
Especially with the bunny's litter box, their urine smells so bad. It the priciest litter, but worth every penny! Our house is closed up all day, so we can judge our cages smells when we walk in at night, and it doesn't smell one little bit, until the evening of day 6. Which is just fine, as I clean them the following day.
I spent $40 on fleece and uhaul furniture pads (3 cage changes!) 16 months ago, and that's been it! I buy a large $20 bag of carefresh every month and I'm set.
I hang the dirty sets outside over a fence in the garden, then I do one big load (2 hours, sanitation cycle) to save water and electricity. We just recently got a HE front loader, and it uses very little water, so I was WORRIED, but on the long cycle, it does better than a top loader filled with water. I'm also too lazy to try to remove all the hair on the fleece first, so I just rinse and wipe the washer after, and run a cleaning cycle once a month to prevent build up. So, don't worry about clean up, it's pretty easy once you find your groove.
We only have 2 boys, but if your cage is big enough for 5, you should have similar results.