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Maybe. I can't tell from the picture. If you want to post something closer up with better lighting, we can better see what you're seeing.
In the meantime, read https://guinealynx.info/pododermatitis.html and see if it looks like any of the pictures.
I wouldn't give the SMZ/TMP for that. GP's don't do well with antibiotics in general, and I'd want to see if it improved with something else first.
Cage cleanliness has way more do to with pododermatitis than weight does. And some pigs prefer to sleep in the same place where they potty. So keep those places especially clean, and discourage her from sleeping in them as much as possible.
The Epsom salts soaks twice a day should be sufficient at this point. I'd hold the chlorhexidine in reserve in case the ES doesn't do the trick. Just make sure you rinse her feet very well after soaking, and don't let her drink the ES water. Upside down bottle caps make good piggy foot baths.
The other thing you might do is apply cold pressed virgin coconut oil to her feet after soaking. It has both antibacterial and antifungal properties, and will lubricate the skin to keep it from cracking.
What kind of bedding is she on?
One more question. To make these fleece sheets work, do I have to wash AND dry them 3-4 times or just wash them 3-4 and then dry them?If you've got her on fleece, make some smaller fleece pads (fleece over towels is fine) and put them in places where she potties. You can change them more often, and they're much easier and quicker to wash than having to change the whole cage every other day.