is this coroplast size big enough?

[SIR PONPON]

is 48in x 96 in x 0.157in to small to make a c&c cage for 2 female guinea pigs?

[lunarminx]

Even if it's too small, most of us just use a strong tape to attach two pieces together. What size c&c are you making?

[lunarminx]

https://www.guineapigcages.com/howtoprint.htm

[lissie]

is 48in x 96 in x 0.157in to small to make a c&c cage for 2 female guinea pigs?

That's not too small. A sheet that size can make up to a 3x6 cage.

For two females, a 2x4 is enough. You can build a larger cage if you have the space.

See this page for how to build the cage.
https://www.guineapigcages.com/howto.htm

[CrystalCavy]

It's probably large enough. 2 females will do fine with a 2x4 cage