Depending on your pig, it could take 1 week to 3 years (or longer) for him/her to be 100% trained. I've had mine for 2 years now and one of them lets me pick him up and pet him for a limit of 30 min at a time. The other I only take out when needed and while I continue to train him he can be out for around 5-7 min. I've come to the conclusion that he will always have trouble being picked up, no matter what. Chances are at least one of your piggies will be like this. When you are ready to start taking them out, I would recommend getting some sort of hide-out area with a bottom. Put some hay or fresh veggies in there and once they walk in pick up the home and set it on your lap. Starting out, you can pet them but don't directly pick them out and take them out of the home in any kind of way. When you first pick up your piggy, use a blanket or fleece so they don't have to come in contact with your skin right away. To feel how stressed they are, lightly feel under their belly or on their neck and check their pulse. As your guinea pigs get used to you, you can take them out for longer periods of time. Make sure no one else holds your pig when you first start out, they need to get used to you first. If you are not yet ready to take you piggies out, continue to hand feed them. Stick you hand in the cage, don't move it, and let them sniff you. Do not chase your piggy around the cage unless you absolutely have to. Spend time by your piggies often. This could be reading by/to them, singing to them, or even telling them about your day. This may sound strange but getting your pigs used to your voice is very important. Make sure you feed them everyday, since food is the key to their trust. If your guinea pigs still continue to not accept food from you, or don't come up to you when you approach their cage, you can turn on some relaxing guinea pig music from YouTube. This works incredibly well. Feel free to ask me any questions about this or another topic. I hoped I helped and I wish you the best of luck for you and your pigs!!