Any reason to spay 2 females?

No it isn't necassary to spay your females. In fact its suggested not to. Its very invasive. I don't beleive that uterine cancer can even happen in a guinea pig. So to answer your question, no.

sorry to double post: I meant that the uterine cancer CAN'T happen in guinea pigs. haha

Sows can get reproductive cancer.

Depending on who you ask about their opinion on routine spaying, you'd get different answers. Spaying is much more invasive than neutering.

I wouldn't do it unless you have a really good vet and your sow is showing reproductive issues.

The rates are not as high as in rabbits.

Alright, thank you, I want long lived, happy piggies, and I want to make sure to check up on everything I can before a pig even sets foot in the house.