Have someone help you to hold her and then get the nail cut. If the entire toe is curled down it could be something a vet needs to see as it could be somehow injured.
There are no sedatives to give without a vet's permission.
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I noticed just a short while ago that she has been hopping around like a rabbit, I know that in 99% of cases that means scurvy
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99% of cases where a pig hopping doesn't necessarily indicate scurvy. There are several indicators other than hopping that indicate a pig has scurvy.